Our Health Library information does not replace the advice of a doctor. Please be advised that this information is made available to assist our patients to learn more about their health. Our providers may not see and/or treat all topics found herein.

Alteplase Injection

This medicine is used for the following purposes:

  • chest pain
  • heart attack
  • stroke
  • treatment of blood clots
  • blood clot

Brand Name(s): Activase

Generic Name: Alteplase

Instructions

This is an IV medicine. It is given through a sterile tube directly into the vein by a healthcare provider.

This medicine should be given by a trained health care provider.

You must be monitored by a health care professional during and after each dose is given.

Drug interactions can change how medicines work or increase risk for side effects. Tell your health care providers about all medicines taken. Include prescription and over-the-counter medicines, vitamins, and herbal medicines. Speak with your doctor or pharmacist before starting or stopping any medicine.

Tell your doctor if symptoms do not get better or if they get worse.

Keep all appointments for medical exams and tests while on this medicine.

Cautions

During pregnancy, this medicine should be used only when clearly needed. Talk to your doctor about the risks and benefits.

Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine.

There is an increased risk of bleeding while on this medicine, please tell your doctor or nurse if you notice any excessive bleeding or bruising.

It is unknown if this medicine passes into breast milk. Ask your doctor before breastfeeding.

Side Effects

Call your doctor or get medical help right away if you notice any of these more serious side effects:

  • bleeding or bruising
  • nosebleeds
  • severe or persistent headache
  • bloody or dark, tarry stools
  • symptoms of stroke (such as one-sided weakness, slurred speech, confusion)
  • blood in urine

A few people may have an allergic reaction to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.

Please speak with your doctor, nurse, or pharmacist if you have any questions about this medicine.

Top of the page